Year 2012, Volume 16, Issue 2, Pages 106 - 112 2012-08-01

Calculation of drug effectiveness on treatment of steatosis hepatis using HOG based ANN.
HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması

Nuh Alpaslan [1] , Muhamed Fatih Talu [2] , Mehmet Gül [3] , Birgül Yiğitcan [4]

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In this work, healing effects of melatonin and resveratrol drugs on liver damage in rats, induced by application of acute and chronic carbon tetrachloride (CCl4) have been examined. The study consists of three main stages: 1) Data Acquisition: 60 rats have been separated into 10 groups. Except control groups other eight groups have been injected olive oil, CCL4 (make liver fatty), CCL4+Melatonin, CCL4+Resveratrol drugs regularly and 4 and 20 days after light microscope images of rats have been obtained from liver tissue.2) Data Processing: By the help of histograms of oriented gradient (HOG) method, obtaining low-dimensional image features (color and shape) and classifying 5 different group characteristics by using these features with artificial neural networks have been provided.3) Calculation of Drug Effectiveness: Firstly to determine the differences between group characteristics of rats, a pilot group has been selected (diseased group-CCl4), and responses of artificial neural networks trained by HOG features have been calculated.As a result, it has been seen that melatonin and resveratrol drugs have %65.62 -%75.12 positive effects at the end of the fourth day, %84.12-%98.89 positive effects on healing steatosis hepatis at the end of the twentieth day respectively.
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Primary Language tr
Subjects Engineering
Published Date Ağustos
Journal Section Research Articles
Authors

Author: Nuh Alpaslan

Author: Muhamed Fatih Talu

Author: Mehmet Gül

Author: Birgül Yiğitcan

Bibtex @research article { saufenbilder220595, journal = {Sakarya University Journal of Science}, issn = {1301-4048}, eissn = {2147-835X}, address = {Sakarya University}, year = {2012}, volume = {16}, pages = {106 - 112}, doi = {10.16984/saufbed.13754}, title = {HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması}, key = {cite}, author = {Alpaslan, Nuh and Talu, Muhamed Fatih and Gül, Mehmet and Yiğitcan, Birgül} }
APA Alpaslan, N , Talu, M , Gül, M , Yiğitcan, B . (2012). HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması. Sakarya University Journal of Science, 16 (2), 106-112. Retrieved from http://www.saujs.sakarya.edu.tr/issue/20672/220595
MLA Alpaslan, N , Talu, M , Gül, M , Yiğitcan, B . "HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması". Sakarya University Journal of Science 16 (2012): 106-112 <http://www.saujs.sakarya.edu.tr/issue/20672/220595>
Chicago Alpaslan, N , Talu, M , Gül, M , Yiğitcan, B . "HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması". Sakarya University Journal of Science 16 (2012): 106-112
RIS TY - JOUR T1 - HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması AU - Nuh Alpaslan , Muhamed Fatih Talu , Mehmet Gül , Birgül Yiğitcan Y1 - 2012 PY - 2012 N1 - DO - T2 - Sakarya University Journal of Science JF - Journal JO - JOR SP - 106 EP - 112 VL - 16 IS - 2 SN - 1301-4048-2147-835X M3 - UR - Y2 - 2012 ER -
EndNote %0 Sakarya University Journal of Science HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması %A Nuh Alpaslan , Muhamed Fatih Talu , Mehmet Gül , Birgül Yiğitcan %T HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması %D 2012 %J Sakarya University Journal of Science %P 1301-4048-2147-835X %V 16 %N 2 %R %U
ISNAD Alpaslan, Nuh , Talu, Muhamed Fatih , Gül, Mehmet , Yiğitcan, Birgül . "HOG tabanlı YSA kullanılarak yağlı karaciğer tedavisindeki ilaç etkinliklerinin hesaplanması". Sakarya University Journal of Science 16 / 2 (August 2012): 106-112.